The global aims of the course "Disease Control and Eradication", of which "Infectious Diseases A" is one part, are to prepare students to a broad understanding of the most common infectious diseases and their clinical management, covering viral, bacterial, fungal, and parasitic diseases. Global epidemiology of the major infectious diseases and public health Implications, including vaccines, will also be covered. Disease control and eradication is divided into the following parts: i) Clinical Epidemiology (Prof MC Monti); ii) Infectious Diseases A (Profs MU Mondelli, R Bruno, and E Petersen); iii) Infectious Diseases B (Prof E Brunetti); iv) The Science of Disease Control and Eradication (Profs R Bruno, E Brunetti, E Petersen). At the end of the course, students should be able to recognize the typical clinical presentations of major infectious diseases and to develop a basic knowledge of the main treatment regimens.
Prerequisiti
Students must have a broad understanding of microbiology and clinical microbiology.
Metodi didattici
Lectures, seminars, bedside teaching, students' presentations, case presentations, revisions.
Verifica Apprendimento
Written examination, open questions, or viva examinations.
Testi
Joseph Loscalzo, Dennis L. Kasper, Anthony S. Fauci, Stephen L. Hauser, Dan L. Longo, J. Larry Jameson, Eds. Harrison's Principles of Internal Medicine, 21st Edition (2022). Chapter “Infectious Diseases”. McGraw Hill Professional.
John E. Bennet, Raphael Dolin, Martin J. Blaser. Mandell, Douglas and Bennet's Principles and Practice of Infectious Diseases, Ninth Edition, (2020). Elsevier. Slide handouts
Contenuti
The following topics are taught in Infectious Diseases A, B, the Science of Disease Control and Eradication: Viral Hepatitis: HAV, HBV, HCV, HDV, HEV Emerging and re-emerging viral infections: Ebola, Zika, Dengue, Chikungunya. COVID-19 and other respiratory infections Invasive fungal infections: Candidiasis, Aspergillosis. The Febrile Patient: Temperature Regulation, Definition of Fuo, Causes of Fuo. Laboratory Studies in Fuo. Treatment of Fever. SIRS and Sepsis: Prevalence, Definitions, Pathogenesis, Clinical Manifestations, Diagnosis, Treatment. Endocarditis. Sexually Transmitted Diseases. Malaria and hints to the most common tropical diseases. Bone and soft tissue infections. HIV Infection: Epidemiology, Definitions, Pathogenesis, Clinical Manifestations, Opportunistic Infection, Diagnosis, Treatment. Infections of the Central Nervous System: Acute and Chronic Meningitis, Encephalitis. Tuberculosis as seen from the infectious disease specialist. TB, MDR, XDR, TDR Mycobacteria. Epidemiology, diagnosis and treatment. General principles of vaccination and types of vaccine.