Understand the basic concepts of immunology and the role of the immune system in protecting the body. Identify the various components of the immune system, including cells, tissues, and organs. Explain the mechanisms of innate and adaptive immune responses. Analyze the cellular and molecular basis of immune recognition and activation. Discuss the interactions between the immune system and infectious agents. Investigate immunological disorders and the underlying causes. Explore different immunotherapies and their applications in disease treatment.
Prerequisiti
Training in the following or related areas: General Biology, Biochemistry, Physics, Calculus, Organic/Inorganic Chemistry. Training in Molecular Biology is recommended but not required.
Metodi didattici
Lectures supported by presentation of slides in Power Point. Key topics will be also supported by specific presentations, discussions and critical reading of the most recent research and review papers published in relevant journals in the field.
Verifica Apprendimento
The student will be given the opportunity to illustrate live and independently the contents, mechanisms and decision-making paths acquired during the course. For this reason, the assessment of learning will take place through a final oral exam in person with a grade expressed out of thirty; there are no ongoing tests. Three questions will be asked: one in a conversational form, one in the form of a direct question and answer and one based on the description of a pattern or a pathological morphofunctional aspect among those illustrated in class and contained in the recommended textbook.
Testi
Abbas A.K, Lichtman A.H., Pillai S. Cellular and Molecular Immunology. International Edition. Tenth edition. Elsevier, 2021.
Contenuti
Properties and Overview of Immune Responses Cells and Tissues of the Immune System Leukocyte Circulation and Migration into Tissues Innate Immunity: inflammatory response Adaptive immunity: the lymphatic system Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues Antigen Presentation to T Lymphocytes and the Functions of MHC Molecules Lymphocyte Development and Antigen Receptor Gene Rearrangement Effector Mechanisms of Humoral Immunity Immunologic Tolerance and Immunopathology