Data di Pubblicazione:
2016
Abstract:
The synthetic pathway towards silyl-substituted nucleoside analogs
is presented and relies upon the 1,3-dipolar cycloaddition
of in situ generated nitrile oxide containing a representative silyl
group. The subsequent synthetic elaborations do not damage
this substituent allowing for the obtaining of the target
compounds. This reliable methodology is prone to be adapted
for the synthesis of silyl derivatives for several applications.
is presented and relies upon the 1,3-dipolar cycloaddition
of in situ generated nitrile oxide containing a representative silyl
group. The subsequent synthetic elaborations do not damage
this substituent allowing for the obtaining of the target
compounds. This reliable methodology is prone to be adapted
for the synthesis of silyl derivatives for several applications.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Nitrile oxides, nitrosocarbonyl, nucleoside, silycon derivatives, organic synthesis
Elenco autori:
Savion, Marco; Bovio, Bruna; Quadrelli, Paolo
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