Comparison of immunologic and molecular assays for the diagnosis of gastrointestinal viral infections.

The performance of immunochromatographic and enzyme-linked immunosorbent assays (RIDA (R) QUICK and RIDASCREEN (R), R-Biopharm) was compared with real-time reverse transcription-polymerase chain reaction techniques for the diagnosis of gastrointestinal viral infections. The sensitivity of the immunologic methods was comparable to polymerase chain reaction for the diagnosis of rotavirus and astrovirus, while it was reduced for detection of norovirus and adenovirus.