Recombinant collagen engineered to bind to discoidin domain receptor functions as a receptor inhibitor

binding; collagen; discoidin domain receptor; inhibition mechanism; peptides; protein chimera; recombinant protein expression; triple-helix; Bacterial Proteins; Binding Sites; Cell Movement; Cells, Cultured; Collagen; Collagen Type III; Fetal Blood; HEK293 Cells; Humans; Immobilized Proteins; Ligands; Megakaryocytes; Peptide Fragments; Protein Engineering; Protein Interaction Domains and Motifs; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptococcus pyogenes; Models, Molecular; Biochemistry; Molecular Biology; Cell Biology