Chloride-binding in organic–water mixtures: the powerful synergy of C–H donor groups within a bowl-shaped cavity

For the first time, the tetrafluorobenzyl unit has been considered as a C–H⋯anion binding motif. In synergy with imidazolium groups within a bowl-shaped receptor, it has allowed for the effective binding of chloride in solution. Remarkable affinity was observed in organic–water mixtures.