Paracheratosi granulare

Granular parakeratosis is an acquired disorder of keratinization of unknown origin affecting mainly flexures of adults. A 48-year-old woman presented a 1-year history of keratotic papules on the infra- and submammary regions. A skin biopsy revealed granular parakeratosis confined to epidermal foci. The patient's eruption resolved completely with topical steroid therapy. Etiopathogenesis and differential diagnosis are discussed.