The potential advantage of omapatrilat: dual anti-fibrotic and antiinflammatory effects in one single molecule

Cardiovascular physiology; Pharmacology; Hypertension; Hypertrophy; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Cell Adhesion Molecules; Drug Therapy; Combination Therapy; Fibrosis; Heart Diseases; Inflammation; Kidney Diseases; Metalloendopeptidases antagonists & inhibitors; Neprilysin antagonists & inhibitors; Phosphonic Acids therapeutic use; Pyridines therapeutic use; Rats; Thiazepines therapeutic use