A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety

amidoximes/oxadiazole/pyridine; FBA; fragments; FRET-melting; G-quadruplex; Drug Design; Drug Evaluation, Preclinical; G-Quadruplexes; HIV Long Terminal Repeat; Heterocyclic Compounds; Ligands; Molecular Structure; Oximes; Small Molecule Libraries; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic Chemistry