Pregnancy outcome and management of 25 pregnancies in women with polycythemia vera.

Our data confirm that pregnant women with PVhave an increased risk of fetal loss. The high rate of advanced miscar-riage, related to the presence ofJAK2V617F mutation, seems to bereduced by anti-thrombotic therapy. The correct use of vene-section has to be established in this setting of patients. Due to the rar-ity of this condition, collaborative studies are required to better clarifythe best management of pregnancy in PV