Data di Pubblicazione:
2020
Abstract:
Camps et al. describe a cell population that blocks fat turnover in the skeletal muscle by single-cell analysis. Furthermore, they show that this population acts through GDF10 secretion and is reduced in dystrophic muscle. This could be an essential turning point in the progressive deterioration of muscular dystrophy patients.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
adipogenesis; GDF10; interstitial stromal cells; muscular dystrophy; single-cell transcriptomics; skeletal muscle
Elenco autori:
Camps, J.; Breuls, N.; Sifrim, A.; Giarratana, N.; Corvelyn, M.; Danti, L.; Grosemans, H.; Vanuytven, S.; Thiry, I.; Belicchi, M.; Meregalli, M.; Platko, K.; Macdonald, M. E.; Austin, R. C.; Gijsbers, R.; Cossu, G.; Torrente, Y.; Voet, T.; Sampaolesi, M.
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