Improved outcomes for kidney transplantation in AL amyloidosis: impact on practice

Effective therapies for Ig light chain (AL) amyloidosis has led to an increasing proportion of patients with end-stage renal disease requiring renal replacement therapy, yet kidney transplantation is seldom performed in this setting due to concerns of renal and extrarenal disease progression. Angel-Korman et al. report unprecedented positive long-term outcomes in the largest series of kidney transplantation in AL amyloidosis providing the basis for a more proactive approach to this procedure.