Diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols with analgesic activity
Articolo
Data di Pubblicazione:
2004
Abstract:
Abstract—The diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols has been accomplished. The diastereoisomers, obtained in high enantiomeric excesses, were investigated by 1H NMR and HPLC analyses. The configurational assignment was performed by NOESY 1H NMR spectroscopy. Pharmacological evaluation of the analgesic activity by means of the hot plate test is described
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
ANALGESIC COMPOUND; OPPIOID; MOUSE
Elenco autori:
Azzolina, Ornella; Collina, Simona; Brusotti, Gloria; Loddo, Guya; Linati, Laura; Lanza, Enrica; Ghislandi, Victor
Link alla scheda completa:
Pubblicato in: