Seizures originating from the temporal lobe and sleep: Clinical and prognostic value of different association pictures

Sleep-related seizures were reported in 64.8% of 111 subjects affected by temporal lobe epilepsy (49 men, 62 women, mean age 47 years, range: 2-60), patients with seizures only during sleep accounting for just 3.6% of the cases. Patients with seizure at onset during sleep, were charactherized, with respect to those with seizure at onset during wakefulness, by further occurrence of subsequent sleep-related seizures in the course of the disease, more frequent secondary generalization of focal seizures and more frequent co-existence of sleep-apnea.