Sarcopenia and homocysteine: is there a possible association in the elderly? A narrative review

Sarcopenia (SA) is a progressive skeletal muscle disorder, associated with increased risk of adverse outcomes, including falls, fractures, physical disability and mortality. Several risks factors may contribute to the development of SA in the elderly; among them, nutrition plays a key role in muscle health. The elderly are at risk of inadequate intake in terms of micronutrients affecting muscle-homeostasis, such as B vitamins, related to homocysteine (Hcy) metabolism.