Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis.
Articolo
Data di Pubblicazione:
2010
Abstract:
The study shows that modification of the DIPSS during
follow-up of PMF patients may also predict different risks of blast phase (BP).
Patients belonging to the higher risk categories have a notable
7.8-fold and 24.9-fold higher risk of developing BP comparing to
those who continue to fit in low-risk category. As BP evolution
implies a dismal outcome, this observation recommends to
approach patients with higher DIPSS categories for intensive or
investigative treatments.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
LEUKEMIA; MYELOFIBROSIS; DIPSS
Elenco autori:
Passamonti, Francesco; Cervantes, F; Vannucchi, Am; Morra, E; Rumi, Elisa; Cazzola, Mario; Tefferi, A.
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