Data di Pubblicazione:
1995
Abstract:
The dioxolenonemethyl moiety of the oral penem prodrug FCE 25199 (1) was found to be a source of photochemical lability in the solid state. Reactions centered on the formation and decomposition of a hydroperoxide (3) have been observed and rationalized.
Expedients have been devised to improve the shelf-life of crystalline 1 up to acceptable levels.
Expedients have been devised to improve the shelf-life of crystalline 1 up to acceptable levels.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
photoreactivity; dioxolenone methyl ester
Elenco autori:
Albini, Angelo; Alpegiani, M.; Borghi, D.; Del Nero, S.; Fasani, Elisa; Perrone, E.
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