Biocompatibility of a new pulp capping cement

Aim. The aim of the present study was to evaluate the biocompatibility of a new pulp capping materi- al (Biodentine, Septodont) compared with refer- ence pulp capping materials: Dycal (Dentsply), ProRoot MTA (Dentsply) and MTA-Angelus (An- gelus) by using murine odontoblast cell line and Alamar blue and MTT cytotoxicity tests. Methods. The citocompatibility of murine odonto- blasts cells (MDPC-23) were evaluated at different times using a 24 Transwell culture plate by Ala- mar blue test and MTT assay. Results. The results were significantly different among the pulp capping materials tested. Bio- compatibility was significant different among ma- terials with different composition. Conclusions. Biodentine and MTA-based prod- ucts show lower cytotoxicity varying from calci- um hydroxide-based material which present high- er citotoxicity