The aim of the course is the acquisition of the basic principles of General Pharmacology (Pharmacokinetics, Pharmacodynamics) and Special Pharmacology, the understanding of drug classes directly and indirectly related to dental practice (their molecular mechanisms, pharmacodinamics and pharmacokinetics, and their therapeutic employment). Lastly the adverse reaction.
Course Prerequisites
Understanding of the basics of Anatomy, Physiology and Biochemistry are needed to better approch the course.
Teaching Methods
Frontal lessons or on-line lessons (according to University of Pavia guidelines). For the conduct of the lectures, PowerPoint presentations are used and made available to the students in the section dedicated to the course on the Moodle platform KIRO.
Assessment Methods
the exam will be a written test to verify the achievement of the educational objectives. Questions will be related to the topics covered during the lessons and under the program. Multiple choices test. Some questions need only one correct answer, other questions need more than one correct answers. The exam will be singular and will consist of a total of 34 questions, 17 related to General Pharmacology and 17 related to Special Pharmacology. The evaluation will be expressed in thirtieths.
Texts
All the material necessary for the preparation of the student will be provided during the course. To in-depth studies, following texts are advised: Bertram G. Katzung Farmacologia Generale e clinica XI Edizione PICCIN
Massimo Collino, Carla Cicala, Armando Ialenti Farmacologia Generale UTET Universitaria
Contents
GENERAL PHARMACOLOGY Definition of Pharmacology and drug, active substance andexcipients. Pharmaceutical forms. Pharmacokinetics: - definitions. - passage of drugs through biological membranes. -Absorption. -bioavailability -routes of administration. -distribution and factors affecting distribution (organ perfusion and volume, ionization and pH, bond with plasma proteins). Drug metabolism. Phase I and II. factors affecting drug metabolism: induction, inibition, genetic polymorphism. Drug excretion and routes of elimination. Pharmacodynamics: Drug mechanisms of action. Receptors. Molecular structure. receptor and drug interactions. Agonists and antagonists, allosteric modulators. Drug interactions. Drug discovery. Evidence-based medicine. SPECIAL PHARMACOLOGY Antibacterial agents. Pain medications. Anticoagulants. Antidepressants and anxiolytics. Statins. Antihypertensives. Antidiabetics. Antineoplastics.
Course Language
Italian
More information
Contact for further information: lauragiuseppina.dipasqua@unipv.it andrea.ferrigno@unipv.it
