The student attending this course is expected to acquire fundamental knowledge of the principles of Presonalized and Precision Medicine, as well as of the underlying techonological advances and understanding of the molecular basis of human diseases. They will be introduced to the process by which new drugs are developed in research laboratories and tested in clinical trials with the important understanding of the involvement of large pharmaceutical industries.
Course Prerequisites
Principles of general biology, genetics, general patology and immunology are required, with particular reference to the mechanisms of cancerogenesis.
Teaching Methods
Lectures and seminars, videos, small group activities, and clinical case discussion.
Assessment Methods
Critical discussion of approaches of Precision Medicine and of the underlying molecular mechanisms. In addition, students will be encouraged to reflect on public aspects of precision medicine, its limitations, and the financial and social consequences of an increasingly technological approach to medicine and healthcare. Learning assessment will include a written assay and an oral discussion (short slide presentation) on precision medicines approaches.
Texts
Teaching material, videos, scientific articles, and many links to sources such as videos online.
Contents
- Principles of Personalized and Precision Medicine: background, definitions and clinical implementation. - Notions of the most relevant biotechnological advances underlying Precision Medicine, in particular next generation sequencing, epigenomic, transcriptomic and proteomic analysis. - Fundamental knowledge of Precision Medicine approaches in rare and common diseases, haematology and Oncology. - Implications of Precision Medicine on basic, translational and clinical research, with reference to new clinical trial design (basket trials, umbrella trials).
Course Language
English
More information
For additional information, please contact the teacher by email or appointment.
