At the end of the course the student will have to know the basic pharmaceutical technology. Students will also have acquired the basic principles necessary to define a pharmaceutical dosage form and to understand the rationale for the formulation of conventional drugs.
Course Prerequisites
Student must have attended the courses, and acquired the basic knowledge, in biochemistry, general and inorganic chemistry.
Teaching Methods
Frontal lessons
Assessment Methods
Learning is verified by written exam. The subject of the examination is the contents of the reference texts and the contents of the lectures.
Texts
Lessons' slides and books. P. Colombo et al. “Principi di tecnologie farmaceutiche”. Casa Editrice Ambrosiana, Milano. A.T. Florence et al. “Physical Pharmacy”. Pharmaceutical Press, London. M.E. Aulton “Pharmaceutics: the Science of Dosage Form Design”. Churchil Livingstone, New York.
Contents
Classification of pharmaceurical dosage forms and administration routes. Principles of biopharmaceutic and pharmakinetic. Bioavailability and bioequivalence. Conventional solid pharmaceutical dosage forms. Pharmaceutical powders characterization. Grinding and mixing. Capsules and tablets (coating methods). Conventional liquid pharmaceutical dosage forms. Solutions and dispersed systems: emulsions and suspensions. Parenteral preparations. Sterilizazion of injectable preparations. Inhalator and pulmonar pharmaceutical dosage forms. pharmaceutical dosage forms for drug controlled release. Site- and time-specific therapeutic systems. Mechanisms for the controll of release rate: reservoir and matrix systems, osmotic pumps.
