Knowledge of the molecular mechanisms related to DNA duplication, gene transcription and protein synthesis. The theoretical acquisition of basic molecular technologies and knowledge of their medical applications.
Course Prerequisites
Knowledge of the structural and functional properties of proteins is required, with particular reference to enzymes.
Teaching Methods
Frontal lessons with the help of PPT.
Assessment Methods
Written exam
Texts
David L. Nelson, Michael M. Cox. Lehninger's principles of biochemistry. Zanichelli.
Denise R. Ferrier The basics of biochemistry Zanichelli
Contents
1. Structure of DNA and RNA. 2. Eukaryotic genes, prokaryotes and human genome. 3. Propagation, conservation and variability of gene information (replication, repair and recombination). 4. Transfer of gene information into RNA (transcription) and maturation of transcripts. 5. Decoding of gene language into proteins (translation). 6. Regulation of gene expression. 7. Recombinant DNA technologies. Transgenic and knock out animals as a model of human diseases and for the study of gene function. 8. Applications of molecular biology in medicine.
Course Language
Italian
More information
The students can get in contact with the professor usingi th fellowing email: nora.bloise@unipv.it
