The course aims to provide the student with knowledge and skills on strategies used in the drug delivery and targeting of active ingredients both of chemical and biotechnological origin. The course aims to provide an overview of the materials and pharmaceutical dosage forms commonly used in the pharmaceutical-technological field.
Course Prerequisites
Basic knowledge of pharmaceutical technology.
Teaching Methods
Lectures carried out remotely, supplemented by multimedia material selected by the teaching. Students will be personally involved through seminars they hold on topics related to the course. For students with specific needs, who cannot attend in person the teaching activities and who have applied for Inclusive Teaching Methods, the professor will provide teaching material suitable for independent study. If requested, self-learning can be supported by supplementary teaching activities and dedicated meetings, also online, with flexible hours depending on the needs.
Assessment Methods
Learning assessment is performed in the form of written test consisting of open questions. The weight of the individual questions in the overall assessment is variable and is detailed in each test. The duration of the test is 2 hours. The results of the tests will be made known through esse3. Appropriate exam modalities are provided for students falling within the categories of Specific Learning Disorders (SLD) and Special Educational Needs (SEN).
Texts
Tecnologia Farmaceutica, P. Caliceti. Casa Editrice Ambrosiana. Principi di Tecnica Farmaceutica, M. Amorosa. Piccin Editore. Tecnologie farmaceutiche. Progettazione e allestimento dei medicinali, M.E. Aulton, K.M.G. Taylor. EDRA LSWR Editore
Contents
Administration routes and bioavailability of drugs. Controlled drug delivery systems classification according to the type of control (temporal, spatial and mixed), according to the type of release mechanism: diffusion controlled systems (reservoir and matrices), chemically controlled systems (biodegradable systems), controlled systems for swelling (swellable matrices) and osmotic pumps. Vesicular controlled delivery systems. Liposomes: advantages and limits, classification, preparation methods, physico-chemical and technological characterization, use in the pharmaceutical field. Microparticles as controlled delivery systems: advantages and limits. Preparation and characterization methods. Use in the pharmaceutical field. Nanoparticles as controlled delivery systems: polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers. Advantages and limits. Physico-chemical and technological characterization. Preparation methods. Use in the pharmaceutical field.
Course Language
Italian
More information
All educational material is provided via the kiro platform.
