Students will learn how to solve problems of poor solubility for small molecules through formulative strategies involving in particular nanoformulation. They will be aware of the relevance of excipient properties and characterization for the pharmaceutical development.
Course Prerequisites
In order to be able to follow the lectures, the student should already have the basic notions of mathematics, chemistry, physics and biology.
Teaching Methods
Classroom lectures. Practical workshops with mandatory attendance and final reports. Classroom exercises with compulsory attendance on the topics covered in the course and a final assessment. To strengthen inclusion of students with specific needs, who cannot attend teaching activities in person and who have applied for Inclusive Teaching Modality, adequate teaching material will be available for fruitful independent study, and if requested, self-learning can be supported by dedicated meetings, including online, with time flexibility depending on needs.
Assessment Methods
1) written essay questions, to evaluate the ability to recognize and analyze the critical aspects of pharmaceutical development steps. 2) short questions. 3) exercises about topics covered in the course. Appropriate examination methods will be adopted for students who of DSA and BES categories.
Texts
Martin A., Physical Pharmacy, Ed. Lea & Febiger; Wells, Pharmaceutical Preformulation, Ed. Horwood; Florence-Atwood, Physico-chemical Principles of Pharmacy, Ed. Macmillan M.E. Aulton, Pharmaceutics, The science of dosage form design. Ed. Churchill-Livingstone Slides will be available in kiro
Contents
Formulation strategies for poorly soluble drugs and nanosystems based on lipid ingredients. Methods to improve solubility of small molecules. Polymeric and lipidic excipient properties and characterization. Drug-excipient compatibility studies.
Course Language
English
More information
All educational material is provided via the kiro platform.
