Red/NIR G-Quadruplex Sensing, Harvesting Blue Light by a Coumarin-Naphthalene Diimide Dyad
Academic Article
Publication Date:
2015
abstract:
A conceptually new light-up nucleic acid fluorescent probe resulting from the conjugation of a coumarin to a naphthalene diimide exhibits a single wavelength emission at 498 nm when free in solution and an additional red/NIR emission when bound to G-quadruplex DNA. The light-up response centred at 666 nm is highly specific for quadruplex DNA when compared to duplex DNA or to RNA quadruplexes.
Iris type:
1.1 Articolo in rivista
Keywords:
G-quadruplexes; dyes; fluorescent probes; naphthalene diimide; nucleic acids
List of contributors:
Zuffo, Michela; Doria, Filippo; Spalluto, Vincenzo; Ladame, Sylvain; Freccero, Mauro
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