MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia
Academic Article
Publication Date:
2014
Iris type:
1.1 Articolo in rivista
Keywords:
Cell Line, Tumor; Cell Nucleus; Cell Transformation, Neoplastic; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 6; Gene Silencing; Humans; Kinesin; Myeloid-Lymphoid Leukemia Protein; Myosins; Oncogene Proteins, Fusion; Protein Transport; Proto-Oncogene Proteins p21(ras); Transcriptional Activation; Translocation, Genetic; Leukemia, Myeloid; Hematology; Biochemistry; Cell Biology; Immunology
List of contributors:
Manara, Elena; Baron, Emma; Tregnago, Claudia; Aveic, Sanja; Bisio, Valeria; Bresolin, Silvia; Masetti, Riccardo; Locatelli, Franco; Basso, Giuseppe; Pigazzi, Martina
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