Targeted single domain antibodies with catalytic activity (T-CAN)

Patent

Publication Date:

2018

abstract:

The present invention is based on the finding that a camelid single domain antibody (sdAb) can be engineered for providing it with asparaginolytic activity; the obtained sdASNase molecule proved to be unexpectedly active and stable and could be targeted onto cancer cells by an antibody.

Iris type:

6.1 Brevetto

Keywords:

T-CAN, catalytic antibodies, asparaginase.

List of contributors:

Scotti, Claudia; Maggi, Maristella

Authors of the University:

MAGGI MARISTELLA

SCOTTI CLAUDIA

Handle:

https://iris.unipv.it/handle/11571/1294766