Targeted single domain antibodies with catalytic activity (T-CAN)

Brevetto
Data di Pubblicazione:
2018
Abstract:
The present invention is based on the finding that a camelid single domain antibody (sdAb) can be engineered for providing it with asparaginolytic activity; the obtained sdASNase molecule proved to be unexpectedly active and stable and could be targeted onto cancer cells by an antibody.
Tipologia CRIS:
6.1 Brevetto
Keywords:
T-CAN, catalytic antibodies, asparaginase.
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://iris.unipv.it/handle/11571/1294766