Reduction of Hospitalizations for Myocardial Infarction in Italy in the COVID-19 Era
Academic Article
Publication Date:
2020
abstract:
Aims: To evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs).
Methods and results: We conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7-32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3-70.3; P < 0.001). Among STEMIs, the reduction was higher for women (41.2%; P = 0.011) than men (17.8%; P = 0.191). A similar reduction in AMI admissions was registered in North Italy (52.1%), Central Italy (59.3%), and South Italy (52.1%). The STEMI case fatality rate during the pandemic was substantially increased compared with 2019 [risk ratio (RR) = 3.3, 95% CI 1.7-6.6; P < 0.001]. A parallel increase in complications was also registered (RR = 1.8, 95% CI 1.1-2.8; P = 0.009).
Conclusion: Admissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates. This constitutes a serious social issue, demanding attention by the scientific and healthcare communities and public regulatory agencies.
Iris type:
1.1 Articolo in rivista
Keywords:
Acute myocardial infarction; COVID-19; Cardiac care units; SARS-CoV2; STEMI.
List of contributors:
S, De Rosa; C, Spaccarotella; C, Basso; Mp, Calabrò; A, Curcio; P, Perrone Filardi; Manconem, ; G, Mercuro; S, Muscoli; S, Nodari; R, Pedrinelli; G, Sinagra; C, Indolfi; Italiana di Cardiologia and the CCU Academy investigators group Società Italiana di Cardiologia and the CCU Academy investigators group: Filippo Angelini, Società; Barillà, Francesco; Bartorelli, Antonio; Benedetto, Francesco; Bernabò, Paola; Bolognese, Leonardo; Briani, Martina; Cacciavillani, Luisa; Calabrese, Alice; Calabrò, Paolo; Caliendo, Luigi; Calò, Leonardo; Casella, Gianni; Casu, Gavino; Cavallini, Claudio; Ciampi, Quirino; Ciccone, Marco; Comito, Michele; Corrada, Elena; Crea, Filippo; D'Andrea, Antonello; D'Urbano, Maurizio; De Caterina, Raffaele; DE FERRARI, Gaetano; De Ponti, Roberto; Della Mattia, Alessio; Di Mario, Carlo; Donnazzan, Luca; Esposito, Giovanni; Fedele, Francesco; Ferraro, Alessandro; Galasso, Gennaro; Galiè, Nazzareno; Gnecchi, Massimiliano; Golino, Paolo; Golia, Bruno; Guarini, Pasquale; Indolfi, Ciro; Leonardi, Sergio; Locuratolo, Nicola; Luzza, Francesco; Manganiello, Vincenzo; Francesca Marchetti, Maria; Marenzi, Giancarlo; Margonato, Alberto; Meloni, Luigi; Metra, Marco; Milo, Marco; Mongiardo, Annalisa; Monzo, Luca; Morisco, Carmine; Nodari, Savina; Novo, Giuseppina; Pancaldi, Stefano; Parollo, Matteo; Paternò, Giovanni; Patti, Giuseppe; Priori, Silvia; Ravera, Amelia; Giuseppe Rebuzzi, Antonio; Rossi, Massimo; Scherillo, Marino; Semprini, Franco; Senni, Michele; Sibilio, Gerolamo; Sinagra, Gianfranco; Siviglia, Massimo; Tamburino, Corrado; Tortorici, Gianfranco; Versace, Francesco; Villari, Bruno; Volpe, Massimo
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