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“Separation and quantification of two beta2-microglobulin isoforms”.

Patent
Publication Date:
2003
abstract:
The present patent refers to a method for the separation and quantification of physiologically relevant isoforms of beta2-microglobulin, in particular of the native form and of its amyloidogenic form, carried out by capillary electrophoresis under temperature-controlled conditions. This separation method faithfully reflects the existing ratios between the said isoforms in physiological solutions, buffers of ionic strength and pH corresponding to these of plasma, serum and urine and allow a precise evaluation of the concentrations present in the samples subjected to analysis
Iris type:
6.1 Brevetto
Keywords:
capillary electrophoresis; isoform; amyloidosis
List of contributors:
Chiti, F; DE LORENZI, Ersilia; Grossi, Silvia; Mangione, Palma; Giorgetti, Sofia; Caccialanza, Gabriele; DOBSON C., M; Merlini, Giampaolo; Ramponi, G; Bellotti, Vittorio
Authors of the University:
BELLOTTI VITTORIO
DE LORENZI ERSILIA
GIORGETTI SOFIA
MANGIONE PALMA
MERLINI GIAMPAOLO
Handle:
https://iris.unipv.it/handle/11571/130067
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