Colocalization of tracks from boron neutron capture reactions and images of isolated cells
Academic Article
Publication Date:
2021
abstract:
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector.
Iris type:
1.1 Articolo in rivista
Keywords:
BNCT; Boron; Cell cultures; Neutron autoradiography
List of contributors:
Postuma, I.; Sommi, P.; Vitali, A.; Shu, D.; Martino, G. D.; Cansolino, L.; Ferrari, C.; Ricci, V.; Magni, C.; Protti, N.; Fatemi, S.; Tamburini, U. A.; Bortolussi, S.; Altieri, S.
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