Publication Date:
2009
abstract:
In the cation formed by photoinduced C−F bond cleavage in fleroxacin, intramolecular reaction with the N−ethyl chain is prevented by the electron-withdrawing effect of fluorine and intermolecular attack by nucleophiles is facilitated.
Iris type:
1.1 Articolo in rivista
Keywords:
fluoroquinolones; fleroxacin; photochemistry; mechanism
List of contributors:
Fasani, Elisa; Monti, Sandra; Manet, Ilse; Tilocca, Fedele; Pretali, Luca; Mella, Mariella; Albini, Angelo
Published in: