Clinical relevance of extra-hematologic comorbidity in the management of patients with myelodysplastic syndrome.

Myelodysplastic syndromes occur mainly in older persons, and these patients are likely to have comorbidities that significantly worsen their survival. In this perspective article, Drs. Della Porta and Malcovati examine the relevance of comorbidities for clinical decision making in patients with myelodysplasti syndromes.