Publication Date:
2009
abstract:
The ESAT-6 (early secreted antigenic target, 6 kDa) family collects small mycobacterial proteins secreted by Mycobacterium tuberculosis, particularly in the early phase of growth. There are 23 ESAT-6 family members in M. tuberculosis H37Rv. In a previous work, we identified the Zur- dependent regulation of five proteins of the ESAT-6/CFP-10 family (esxG, esxH, esxQ, esxR, and esxS). esxG and esxH are part of ESAT-6 cluster 3, whose expression was already known to be induced by iron starvation.
Iris type:
1.1 Articolo in rivista
Keywords:
Antigens, Bacterial; Bacterial Proteins; Base Sequence; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydrogen-Ion Concentration; Iron; Molecular Sequence Data; Mycobacterium smegmatis; Promoter Regions, Genetic; RNA, Bacterial; RNA, Messenger; Stress, Physiological; Transcription Initiation Site; Transcription, Genetic; Multigene Family
List of contributors:
Maciag, Anna; Piazza, Aurora; Riccardi, Giovanna; Milano, Anna
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