The 'GGCC' haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera.

Academic Article

Publication Date:

2009

abstract:

Findings of this study provide evidence that the increased susceptibility to somatic mutagenesis exhibited by the JAK2 GGCC haplotype is not restricted to JAK2-V617F, but also includes the less frequent but more diverse JAK2 exon 12 mutations.

Iris type:

1.1 Articolo in rivista

Keywords:

Myeloproliferative neoplasms; JAK2; mutagenesis

List of contributors:

Olcaydu, D; Skoda, Rc; Looser, R; Li, S; Cazzola, Mario; Pietra, D; Passamonti, Francesco; Lippert, E; Carillo, S; Girodon, F; Vannucchi, A; Reading, Ns; Prchal, Jt; Ay, C; Pabinger, I; Gisslinger, H; Kralovics, R.

Handle:

https://iris.unipv.it/handle/11571/150492

Published in:

LEUKEMIA

Journal

Overview

URL

http://www.nature.com/leu/journal/vaop/ncurrent/abs/leu2009110a.html

The 'GGCC' haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera.

Olcaydu, D; Skoda, Rc; Looser, R; Li, S; Cazzola, Mario; Pietra, D; Passamonti, Francesco; Lippert, E; Carillo, S; Girodon, F; Vannucchi, A; Reading, Ns; Prchal, Jt; Ay, C; Pabinger, I; Gisslinger, H; Kralovics, R.

LEUKEMIA

Overview

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