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Concomitant Resistance to Cefiderocol and Ceftazidime/Avibactam in Two Carbapenemase-Producing Klebsiella pneumoniae Isolates from Two Lung Transplant Patients

Academic Article
Publication Date:
2024
abstract:
: In this study, we present two cases of Klebsiella pneumoniae, one KPC-33- and one NDM-1-producing, showing resistance to cefiderocol and ceftazidime/avibactam, collected in the intensive care unit of a hospital in Northern Italy from two patients who had recently undergone lung transplantation. Whole-genome sequencing was performed to investigate the molecular features of these strains.
Iris type:
1.1 Articolo in rivista
Keywords:
KPC mutated; Klebsiella pneumoniae; blaKPC-33; blaNDM-1; cefiderocol; cefiderocol resistance; ceftazidime/avibactam; ceftazidime/avibactam resistance; co-resistance; virulence factors
List of contributors:
Bellinzona, Greta; Merla, Cristina; Corbella, Marta; Iskandar, Elizabeth Nagy; Seminari, Elena; Di Matteo, Angela; Gaiarsa, Stefano; Petazzoni, Greta; Sassera, Davide; Baldanti, Fausto; Piazza, Aurora; Cambieri, Patrizia
Authors of the University:
BALDANTI FAUSTO
Bellinzona Greta
ISKANDAR ELIZABETH NAGY ROSHDY
PIAZZA AURORA
SASSERA DAVIDE
Handle:
https://iris.unipv.it/handle/11571/1489096
Published in:
MICROBIAL DRUG RESISTANCE
Journal
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URL

https://www.liebertpub.com/doi/10.1089/mdr.2023.0054?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0pubmed
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