ID:
506518
Durata (ore):
16
CFU:
2
SSD:
PATOLOGIA GENERALE
Anno:
2025
Dati Generali
Periodo di attività
Secondo Semestre (02/03/2026 - 29/05/2026)
Syllabus
Obiettivi Formativi
At the successful conclusion of this module, you should be able to demonstrate the following Module level Learning Outcomes (MLOs):
MLO.1 Knowledge and Understanding.
You will be able to explain biological mechanisms of organ/system dysfunction in disease, altered physiology, disease causes and progression, and links to clinical signs.
MLO.2 Application of Knowledge
You will be able to apply knowledge of altered physiology to explain disease, analyze clinical cases, and use lab and simulation exercises to reinforce learning.
MLO.3 Autonomy of Judgement
You will be able to make informed judgments on complex pathophysiological changes and reflect on common mechanisms like inflammation and ischemia.
MLO.4 Communication Skills
You will be able to communicate pathophysiological concepts clearly and present interpretations of altered physiology.
MLO.5 Learning Skills
You will be able to navigate lectures, practicals, and online tools, integrating pathophysiology with related modules to support clinical reasoning.
MLO.1 Knowledge and Understanding.
You will be able to explain biological mechanisms of organ/system dysfunction in disease, altered physiology, disease causes and progression, and links to clinical signs.
MLO.2 Application of Knowledge
You will be able to apply knowledge of altered physiology to explain disease, analyze clinical cases, and use lab and simulation exercises to reinforce learning.
MLO.3 Autonomy of Judgement
You will be able to make informed judgments on complex pathophysiological changes and reflect on common mechanisms like inflammation and ischemia.
MLO.4 Communication Skills
You will be able to communicate pathophysiological concepts clearly and present interpretations of altered physiology.
MLO.5 Learning Skills
You will be able to navigate lectures, practicals, and online tools, integrating pathophysiology with related modules to support clinical reasoning.
Prerequisiti
The prerequisites are indicated in the Integrated Course Syllabus for BOD.
Metodi didattici
Teaching methods include lectures, discussion and guided independent study.
Lectures present key concepts (supports CLO.1, CLO.2) and include interactive discussion of clinical cases (supports CLO.2-3), guided readings and the e-learning platform (supports CLO.5).
Teaching will include guidance to help you prepare for the exam (supports CLO.4) and throughout you will be presented with references to further readings and other materials to support your development (supports CLO.5).
Lectures present key concepts (supports CLO.1, CLO.2) and include interactive discussion of clinical cases (supports CLO.2-3), guided readings and the e-learning platform (supports CLO.5).
Teaching will include guidance to help you prepare for the exam (supports CLO.4) and throughout you will be presented with references to further readings and other materials to support your development (supports CLO.5).
Verifica Apprendimento
The assessment process is indicated in the Integrated Course Syllabus for BOD.
Testi
The examination paper is based on the content of the module(s) as taught. It is difficult to a suggest comprehensive single text, as most "General Pathophysiology" titles include several chapters on Medical Pathophysiology, which is not the subject of this module, and sometimes fail to include important aspects of General Pathophysiology.
Individual chapters in the texts below, however, will be useful for the purposes of revision and exam preparation.
Suggested texts:
- Leach R. Acute and Critical Care Medicine at a Glance. 2nd ed. Wiley and Sons; 2009, especially for Alterations of Oxygenation.
- Davenport HW. The ABC of Acid-Base Chemistry. University of Chicago Press.
- Kamel KS, Halperin ML. Fluid, Electrolyte and Acid-Base Physiology: A Problem-Based Approach. 5th ed. Elsevier; 2016.
Additional materials, including selected scientific articles will be distributed via the KIRO e-learning platform
Individual chapters in the texts below, however, will be useful for the purposes of revision and exam preparation.
Suggested texts:
- Leach R. Acute and Critical Care Medicine at a Glance. 2nd ed. Wiley and Sons; 2009, especially for Alterations of Oxygenation.
- Davenport HW. The ABC of Acid-Base Chemistry. University of Chicago Press.
- Kamel KS, Halperin ML. Fluid, Electrolyte and Acid-Base Physiology: A Problem-Based Approach. 5th ed. Elsevier; 2016.
Additional materials, including selected scientific articles will be distributed via the KIRO e-learning platform
Contenuti
The General Pathophysiology module of the Harvey course emerged from the Italian Golgi degree programme in Medicine and Surgery at Pavia which has been taught for more than a decade by Prof. Vanio Vannini, my teacher and mentor. This course is largely built on all the teaching material he collected throughout his career and is intended to maintain and communicate his vision of the subject.
Topics you will study in this module include:
• Homeostasis, functional insufficiency.
• Alterations in homeostasis of the following functions: psycho-neuro-endocrine-immunological, oxygenation, water and sodium, acid-base and potassium ion.
A consistent structure will be maintained throughout each block: a definition of the function under consideration followed by the list of the organs and systems involved in its regulation and performance and the main regulatory mechanisms, and a discussion of the alterations of each function and of their clinical significance. Clinical examples will be supplied and exercises will be proposed when considered useful for a better understanding of the key concepts.
This module will introduce you to some of the most important questions concerning integrated functions. In each section, we will define and then review the main regulatory mechanism of each function. Alterations of function are determined by physiological and pathological conditions, which we will discuss alongside the corresponding pathophysiological models.
A core focus of this module will be on:
(a) the relevant experimental systems, fundamental and necessary for the definition of the pathophysiological mechanisms involved (i.e., “how it works”) and
(b) the clinical context, the final context in which knowledge acquired through the module will be applied in everyday work (i.e., the place where you will use your understanding of how every function works to make sense of the complex reality represented by the condition of an individual patient).
In this perspective, this pathophysiology course is intended as a preliminary bridge between laboratory science and clinical work and is intended to provide you with the opportunity to start building relationships between most of the basic disciplines, on the one hand, and the clinical disciplines, on the other, where you will become accustomed with the process of “reading” and treating the patient.
Topics you will study in this module include:
• Homeostasis, functional insufficiency.
• Alterations in homeostasis of the following functions: psycho-neuro-endocrine-immunological, oxygenation, water and sodium, acid-base and potassium ion.
A consistent structure will be maintained throughout each block: a definition of the function under consideration followed by the list of the organs and systems involved in its regulation and performance and the main regulatory mechanisms, and a discussion of the alterations of each function and of their clinical significance. Clinical examples will be supplied and exercises will be proposed when considered useful for a better understanding of the key concepts.
This module will introduce you to some of the most important questions concerning integrated functions. In each section, we will define and then review the main regulatory mechanism of each function. Alterations of function are determined by physiological and pathological conditions, which we will discuss alongside the corresponding pathophysiological models.
A core focus of this module will be on:
(a) the relevant experimental systems, fundamental and necessary for the definition of the pathophysiological mechanisms involved (i.e., “how it works”) and
(b) the clinical context, the final context in which knowledge acquired through the module will be applied in everyday work (i.e., the place where you will use your understanding of how every function works to make sense of the complex reality represented by the condition of an individual patient).
In this perspective, this pathophysiology course is intended as a preliminary bridge between laboratory science and clinical work and is intended to provide you with the opportunity to start building relationships between most of the basic disciplines, on the one hand, and the clinical disciplines, on the other, where you will become accustomed with the process of “reading” and treating the patient.
Lingua Insegnamento
INGLESE
Altre informazioni
For further information please see the Integrated Course Syllabus for BOD.
Corsi
Corsi
MEDICINE AND SURGERY
Laurea Magistrale Ciclo Unico 6 Anni
6 anni
No Results Found
Persone
Persone
No Results Found