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  1. Insegnamenti

500458 - BIOCHEMISTRY

insegnamento
ID:
500458
Durata (ore):
62
CFU:
6
SSD:
BIOCHIMICA
Anno:
2025
  • Dati Generali
  • Syllabus
  • Corsi
  • Persone

Dati Generali

Periodo di attività

Secondo Semestre (02/03/2026 - 12/06/2026)

Syllabus

Obiettivi Formativi

The Biochemistry course will focus on the specific metabolic pathways of selected tissues and organs—including bone, cartilage, lung, and muscle—examining their regulation and integration within the broader metabolic network. The biochemical basis of both common and rare pathologies will be explored in light of the most recent scientific discoveries. The course has the following main objectives: 1. To complete and deepen the metabolic framework introduced in the undergraduate Biochemistry course; 2. To develop a comprehensive understanding of metabolic pathways and their regulation in an integrated physiological context, with particular emphasis on intracellular signaling mechanisms; 3. To provide in-depth knowledge of the tissue- and organ-specific metabolic processes examined, and to discuss the clinical consequences of their dysregulation. Two CFU will be allocated to a Journal Club activity. Students will be divided into two main groups, each further split into subgroups of five students. During the Journal Club, each subgroup will conduct an in-depth analysis of a selected scientific paper. The paper will then be presented in a flipped classroom format, fostering active discussion and critical evaluation among peers.

Prerequisiti

A solid understanding of general biochemistry is required, including protein structure and function, regulation of enzyme activity, membrane composition and transport mechanisms, as well as the fundamentals of signal transduction pathways and metabolic processes. A basic familiarity with biochemical and imaging techniques is also recommended.

Metodi didattici

The course is delivered through traditional lectures supported by PowerPoint presentations, which are made available to students on the Kiro platform. In addition, group-based discussion workshops will be conducted to encourage theoretical application of concepts. These workshops will focus on topics aligned with the course content and selected by the professor. The course includes a Journal Club activity, where groups of students will conduct an in-depth analysis of a selected scientific paper. Each group will then present the paper in a flipped classroom format, encouraging active participation, peer-to-peer learning, and critical evaluation of the content. This approach fosters deeper understanding and enhances the development of scientific reasoning and discussion skills.

Verifica Apprendimento

The final grade will be assigned out of 30 points, with the possibility of honors. The evaluation includes both a written and an oral component. The written exam has a maximum score of 20 points, divided into 15 points for "Biochemical Mechanisms and Signaling" (Prof. Forlino) and 5 points for "Biochemical and Molecular Basis of Diseases" (Prof. Besio). The Journal Club activity will be assessed through an oral presentation of selected scientific publications at the end of the discussion workshops. Presentations, supported by PowerPoint slides, carry a maximum of 10 points.

Testi

-David L. Nelson, Michael M. Cox: "Lehninger's principles of biochemistry" Ed. Zanichelli -C. Marcello Caldarera: "Human Systematic Biochemistry" CLUEB -Selected scientific articles will be indicated during the lectures and made available to students through the Kiro platform.

Contenuti

For each organ, the course will present its general functions, the main metabolic pathways, and key signal transduction mechanisms. Special emphasis will be placed on the biochemical interactions and cross-talk between different organs. The clinical implications of dysfunctions in bone, cartilage, lung, and muscle will be explored, with a selection of pathologies updated annually based on the latest scientific discoveries. Course topics include: • Biochemical mechanisms underlying metabolic pathways in bone, cartilage, lung, and muscle • Signal transduction pathways in these tissues and their regulatory roles • Biochemical and molecular basis of bone, cartilage, muscle and lung diseases, with particular focus on both rare and common conditions

Lingua Insegnamento

INGLESE

Corsi

Corsi

MEDICAL AND PHARMACEUTICAL BIOTECHNOLOGIES 
Laurea Magistrale
2 anni
No Results Found

Persone

Persone (2)

BESIO ROBERTA
Settore BIOS-07/A - Biochimica
AREA MIN. 05 - Scienze biologiche
Gruppo 05/BIOS-07 - BIOCHIMICA
Professore associato
FORLINO ANTONELLA
Settore BIOS-07/A - Biochimica
AREA MIN. 05 - Scienze biologiche
Gruppo 05/BIOS-07 - BIOCHIMICA
Professore Ordinario
No Results Found
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