ID:
509945
Durata (ore):
52
CFU:
6
SSD:
Biochimica clinica e biologia molecolare clinica
Anno:
2026
Dati Generali
Periodo di attività
Primo Semestre (28/09/2026 - 15/01/2027)
Syllabus
Obiettivi Formativi
At the successful completion of this module, students will be able to demonstrate the following learning outcomes:
Knowledge and Understanding
You will acquire an advanced understanding of the biochemical and molecular mechanisms underlying physiological and pathological processes, together with the principles and clinical applications of major laboratory tests used in medical diagnostics.
Application of Knowledge
You will be able to apply biochemical and biotechnological knowledge to the selection and interpretation of laboratory investigations in relevant clinical scenarios. You will use quantitative data, reference intervals, and appropriate analytical parameters to evaluate laboratory results.
Autonomy of Judgement
You will develop the ability to critically evaluate the diagnostic performance and clinical relevance of laboratory tests, taking into account disease prevalence, sensitivity, specificity, predictive values, analytical variability, and potential sources of error or limitation.
Learning Skills
You will develop the ability to independently update and expand your knowledge of clinical biochemistry and laboratory medicine through the critical analysis of scientific literature, clinical case studies, databases, and digital learning resources.
Knowledge and Understanding
You will acquire an advanced understanding of the biochemical and molecular mechanisms underlying physiological and pathological processes, together with the principles and clinical applications of major laboratory tests used in medical diagnostics.
Application of Knowledge
You will be able to apply biochemical and biotechnological knowledge to the selection and interpretation of laboratory investigations in relevant clinical scenarios. You will use quantitative data, reference intervals, and appropriate analytical parameters to evaluate laboratory results.
Autonomy of Judgement
You will develop the ability to critically evaluate the diagnostic performance and clinical relevance of laboratory tests, taking into account disease prevalence, sensitivity, specificity, predictive values, analytical variability, and potential sources of error or limitation.
Learning Skills
You will develop the ability to independently update and expand your knowledge of clinical biochemistry and laboratory medicine through the critical analysis of scientific literature, clinical case studies, databases, and digital learning resources.
Metodi didattici
Teaching methods include lectures, discussion and guided independent study. Lectures present key concepts (supports LO.1, LO.2), facilitate interactive discussion of clinical cases and laboratory approaches (supports LO.2-3) and are supported by the e-learning platform (supports LO.4). Teaching will include guidance to help you prepare for the exam and throughout you will be presented with references to further readings and other materials to support your development (supports LO.4). In addition, a dedicated seminar cycle conducted by Prof. Gromiha will provide students with advanced and specialized perspectives on protein bioinformatics, with particular emphasis on sequence–structure–function relationships.
Verifica Apprendimento
This module course is assessed by a single written integrated exam.
Structure: Multiple-Choice Question examination
31 Multiple-Choice Questions, each worth 1 mark. These questions assess learning across the entire module.
Assessment criteria and Final Grade Calculation
Each correct answer is worth 1 mark (=1/30 on a 0-30L grading scale)
There is no penalty for incorrect or unanswered questions
A passing mark for examination is 18/30 (=18 correct answers)
If you answer 31 questions correctly questions correctly (=31/30) you will earn you a final grade of 30 “lode” (with honours)
Additional Guidance
Any detected academic misconduct will result in a zero score for the examination.
Structure: Multiple-Choice Question examination
31 Multiple-Choice Questions, each worth 1 mark. These questions assess learning across the entire module.
Assessment criteria and Final Grade Calculation
Each correct answer is worth 1 mark (=1/30 on a 0-30L grading scale)
There is no penalty for incorrect or unanswered questions
A passing mark for examination is 18/30 (=18 correct answers)
If you answer 31 questions correctly questions correctly (=31/30) you will earn you a final grade of 30 “lode” (with honours)
Additional Guidance
Any detected academic misconduct will result in a zero score for the examination.
Testi
Tietz NW, Rifai N, Horvath AR, et al. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th ed. Elsevier; 2012.
Additional materials, including selected scientific articles will be distributed via the KIRO e-learning platform
Additional materials, including selected scientific articles will be distributed via the KIRO e-learning platform
Contenuti
The course is designed to provide students with a solid understanding of the biochemical and molecular tools required for preventive, diagnostic, and therapeutic interventions in both hereditary and acquired disorders. Emphasis is placed on developing the ability to select and interpret laboratory tests appropriately within specific clinical contexts, taking into account factors such as disease prevalence and diagnostic performance.
The program covers key areas of Laboratory Medicine, including monoclonal gammopathies, cardiology, nephrology, liver diseases, endocrinology, and disorders of bone and calcium metabolism. Additional topics include coagulation, tumor markers, and the role of plasma proteins as indicators of disease.
Finally, the course introduces students to the development of novel biomarkers, with a focus on emerging approaches in clinical proteomics and genomics, highlighting their growing importance in modern diagnostic practice.
A dedicated seminar cycle conducted by Prof. Gromiha will provide students with advanced and specialized perspectives on protein bioinformatics, with particular emphasis on sequence–structure–function relationships. The seminar cycle will cover computational approaches to protein stability, folding, aggregation, and molecular interactions involving proteins, nucleic acids, and carbohydrates. It will also address the development and application of bioinformatics databases and computational tools to investigate the molecular basis of diseases, predict the effects of mutations, and support the identification of potential therapeutic targets.
Particular attention will be given to the integration of computational biology with clinical and biochemical applications, including biomarker discovery, proteomics, and genomics. The seminars will enable students to connect theoretical knowledge with practical and translational applications in biomedical research, with examples drawn from complex diseases including cancer, neurodegenerative, and infectious disorders.
The program covers key areas of Laboratory Medicine, including monoclonal gammopathies, cardiology, nephrology, liver diseases, endocrinology, and disorders of bone and calcium metabolism. Additional topics include coagulation, tumor markers, and the role of plasma proteins as indicators of disease.
Finally, the course introduces students to the development of novel biomarkers, with a focus on emerging approaches in clinical proteomics and genomics, highlighting their growing importance in modern diagnostic practice.
A dedicated seminar cycle conducted by Prof. Gromiha will provide students with advanced and specialized perspectives on protein bioinformatics, with particular emphasis on sequence–structure–function relationships. The seminar cycle will cover computational approaches to protein stability, folding, aggregation, and molecular interactions involving proteins, nucleic acids, and carbohydrates. It will also address the development and application of bioinformatics databases and computational tools to investigate the molecular basis of diseases, predict the effects of mutations, and support the identification of potential therapeutic targets.
Particular attention will be given to the integration of computational biology with clinical and biochemical applications, including biomarker discovery, proteomics, and genomics. The seminars will enable students to connect theoretical knowledge with practical and translational applications in biomedical research, with examples drawn from complex diseases including cancer, neurodegenerative, and infectious disorders.
Lingua Insegnamento
INGLESE
Altre informazioni
For further information please see the Integrated Course syllabus
Corsi
Corsi
MEDICAL AND PHARMACEUTICAL BIOTECHNOLOGIES
Laurea Magistrale
2 anni
No Results Found
Persone
Persone (4)
Docente
No Results Found