Definition of “Orthodontics and maxillo-facial orthopaedics”; preventive, interceptive, and fixed orthodontics – possibilities and limits of the treatment in various age groups patients . Deciduous, mixed and permanent dentition; the evolution of the arches; normal occlusion in deciduous and permanent dentition. Skeletal and dental malocclusions; malocclusions in deciduous, mixed and permanent dentition. Skeletal and dento-alveolar transversal problems: diagnosis and therapy notes. Skeletal and dento-alveolar sagittal problems: diagnosis and therapy notes. Skeletal and dento-alveolar vertical problems: diagnosis and therapy notes. Dental movements: notes of biology and biomechanics. Multibrackets fixed appliances; invisible aligners. Orthodontic fixed therapy in parodontal compromised patiens. Retention therapy.