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  1. Courses

501705 - KIDNEY PHYSIOLOGY

courses
ID:
501705
Duration (hours):
16
CFU:
2
SSD:
FISIOLOGIA
Year:
2025
  • Overview
  • Syllabus
  • Degrees
  • People

Overview

Date/time interval

Primo Semestre (01/10/2025 - 16/01/2026)

Syllabus

Course Objectives

The course will teach students the phenomena occurring at molecular, cellular, tissue and organ level which support vital functions. At the end of the course, students will know how the organs and systems of the human body work, how their cooperate, and how their function is controlled to keep homeostasis. What is taught at all level of organisation of the living matter will be pout in the frame of the way the organism works. Students will learn the major correlations between the phenomena occurring in physiologic and pathologic conditions.

Course Prerequisites

The student of the Human Physiology course are required the following knowledge and skills:
- mathematics: knowledge of mathematics at secondary school level supplemented
by the skills acquired in the teaching of Medical Physics in the first year of the course
- physics: all the skills acquired in the teaching of Medical Physics in the first year of
the course with particular regard to the biophysical approach to the function of
tissues and organs.
- biology: physics skills at secondary school level supplemented by all the skills
acquired in the Biology teaching of the 1st year of the course with particular regard to
the genetic code, its transmission and mutations
- histology: all the knowledge acquired in the teaching of Histology and Embryology
in the first year of the course with particular regard to cellular functions and the
structure of tissues and organs.

- anatomy: all the knowledge acquired in the teaching of Human Anatomy in the first
year of the course with particular emphasis on the structure of organs and their
functional anatomy. Passing the Anatomy examination is a prerequisite for the
Human Physiology examination.
- biochemistry: all the skills acquired in the Biochemistry course of the first year with
particular emphasis on the metabolic pathways of energy metabolism, mitochondrial
function, the structure of proteins and their synthesis and degradation. Passing the
Biochemistry examination is a prerequisite for the Physiology examination.

Teaching Methods

Lectures, rehearsal and questions and answers to the class

Assessment Methods

For further information please see the Integrated Course Syllabus for “[506512] - FUNCTIONS OF THE BODY”

Texts

One of the following books:

Vander's Human Physiology, 14th Edition - McGraw Hill

Ganong's Review of Medical Physiology, 25th Edition - McGraw Hill

Berne & Levy Physiology, 6th Edition - Elsevier

Contents

Basic Principles of Renal Physiology
Renal Functions
Structure of the Kidneys and Urinary System
Basic Renal Processes
Glomerular Filtration
Tubular Reabsorption
Tubular Secretion
Metabolism by the Tubules
Regulation of Membrane Channels and Transporters
“Division of Labor” in the Tubules
The Concept of Renal Clearance
Micturition
Incontinence
Regulation of Ion and Water Balance
Total-Body Balance of Sodium and Water
Basic Renal Processes for Sodium and Water
Primary Active Na+ Reabsorption
Coupling of Water Reabsorption to Na Reabsorption
Urine Concentration: The Countercurrent Multiplier System
Renal Sodium Regulation
Control of GFR
Control of Na+ Reabsorption
Renal Water Regulation
Osmoreceptor Control of Vasopressin Secretion
Baroreceptor Control of Vasopressin Secretion
The Response to Sweating
Thirst and Salt Appetite
Potassium Regulation
Renal Regulation of K+
Renal Regulation of Calcium and Phosphate Ion
Diuretics
Hydrogen Ion Regulation
Sources of Hydrogen Ion Gain or Loss
Buffering of Hydrogen Ion in the Body
Integration of Homeostatic Controls
Renal Mechanisms
H2CO3 Handling
Addition of New HCO 3 to the Plasma
Renal Responses to Acidosis and Alkalosis
Classification of Acidosis and Alkalosis

Course Language

English

More information

- The course offers tutoring focused on in-depth analysis and further understanding of the topics taught

Degrees

Degrees

MEDICINE AND SURGERY 
Single-cycle Master’s Degree (6 Years)
6 years
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People

People

LEFKIMMIATIS KONSTANTINOS
AREA MIN. 05 - Scienze biologiche
Gruppo 05/BIOS-06 - FISIOLOGIA
Settore BIOS-06/A - Fisiologia
Professore Ordinario
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