ID:
501309
Duration (hours):
40
CFU:
5
SSD:
PATOLOGIA GENERALE
Year:
2025
Overview
Date/time interval
Secondo Semestre (02/03/2026 - 19/06/2026)
Syllabus
Course Objectives
The General Pathology course aims to provide an integrated understanding of the biological mechanisms underlying the most relevant human diseases. The course will explore cellular adaptation to stress, the dynamics of cellular and tissue injury, and the different forms of cell death.
Inflammation will be addressed in its cellular, molecular, and systemic components. Particular focus will be dedicated to the study of the immune system and major immune-mediated diseases.
Finally, the course will cover the mechanisms involved in vascular pathology as well as the processes associated with tumorigenesis.
By the end of the course, students will be able to:
Identify the main causes of alterations in human biological structures and functions.
Understand the molecular mechanisms of cellular and tissue damage underlying the onset of major human diseases.
Apply the acquired knowledge to rationally identify potential therapeutic targets.
Course Prerequisites
Basics of chemistry, biochemistry and physiology, molecular and cellular biology, genetics, anatomy and histology.
Teaching Methods
The course consists of frontal lectures by using PowerPoint presentations. Teachers are available for any explanation of the topics covered in the course during office hours.
Assessment Methods
Assessment of Learning
Student learning will be assessed through a written examination designed to verify the knowledge and competencies acquired during the course. The Faculty reserves the right to request an oral examination.
Students will be evaluated through a multiple-choice examination (MCE).
The exam will consist of 21 questions, with 1.5 points assigned for each correct answer and no penalty for incorrect answers.
The exam will include short questions and case-based clinical questions, distributed as follows:
Cellular pathology: 3–4 questions
Inflammation: 6 questions
Vascular pathology: 3–4 questions
Tumor biology: 4 questions
Immunopathology: 6 questions
To successfully pass the General Pathology module, students must obtain a minimum score of 18 points.
Students who answer all questions correctly (31.5 points) will receive the final grade of 30 with Lode.
Texts
Kumar V, Abbas AK, Aster J. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Elsevier; 2020.
Abbas AK, Lichtman AH, Pillai S S. Cellular and Molecular Immunology. 10th ed. Elsiever; 2021
Contents
CELLULAR PATHOLOGY
1.Cellular adaptation and stress responses
2. Mechanisms of cell injury and pathways of cell death
INFLAMMATION
3. Hematopoiesis and inflammatory cells
4. Soluble mediators of inflammation
5. Leukocyte migration and acute inflammatory responses
6. Chronic inflammation, tissue repair, and fibrosis
7. Mechanisms of pathogen elimination
VASCULAR PATHOLOGY
8. Angiogenesis and vascular remodeling
9. Thrombotic diseases and atherosclerosis
TUMOR BIOLOGY
10. Principles of tumor biology
11. Classification of benign and malignant neoplasms
12. Molecular mechanisms of cancer –13. Clinical implications of tumors
IMMUNOPATHOLOGY
14. Hypersensitivity reactions
15. Hypersensitivity reactions and autoimmune diseases
16. Transplant rejection and primary immunodeficiencies
17. Tumor immunology and emerging immunotherapies
Course Language
Italian
More information
All teachers involved in the course are available for explanation on covered topics upon appointment taken by email.
Degrees
Degrees
MEDICINAL CHEMISTRY AND PHARMACEUTICAL TECHNOLOGY
Single-cycle Master’s Degree
5 years
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People
People
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