The aim of this course is to provide a suitable information concerning the role and structural properties of drugs important for their biological activity and toxicity
Teaching Methods
Frontal classes performed with informatic support (Slides).
Assessment Methods
Partial examination will be performed during the course (in itinere) Conditions for approving the course: Sufficiency in written tests Parts A and B/C (in the official examination dates) by means of a computer-based test for admission to the subsequent oral examination.
Texts
All material used by the teacher during the lectures will be provided in the Kiro web site Lemke & Williams “Foye’s Principi di Chimica Farmaceutica”, Piccin. Patrick GL “Introduzione alla Chimica farmaceutica” Edises.
Contents
Part A: General medicinal chemistry Design of new drugs and structure activity relationship. Mechanisms of action of drugs. Chemical, physical and biopharmaceutical properties of drugs and pharmacokinetic. Metabolism of drugs.
Part B. Drugs of peripheral organs and systems. Drugs active on peripheral nervous system. Drugs for respiratory system. Drugs for gastro-enteric system. Drugs for cardio-circulatory system.
Part C. Drugs for pain treatment and active on the central nervous system. FANS and drug used for the treatment of migraine. Drugs for the treatment of pain: local anaesthetic and opioids. Psychiatric drugs and drugs of abuse Neurological drugs: anti-spastic, anti-Parkinson and drugs used in the treatment of Alzheimer desease
