ID:
501359
Duration (hours):
96
CFU:
12
SSD:
FARMACOLOGIA
Year:
2025
Overview
Date/time interval
Secondo Semestre (02/03/2026 - 19/06/2026)
Syllabus
Course Objectives
The toxicology and pharmacovigilance course is focused to provide knowledge on 1) the basic problems of toxicology and of the in vivo and in vitro tests usually employed to evaluate the toxic potential of different molecules; 2) the pharmacovigilance (detection, assessment, understanding and prevention of adverse effects or any other medicine-related problem), and 3) the mechanisms guiding to drug interactions useful to manage cases in the real life as well as in a pharmacy.
Course Prerequisites
The student must possess the basic knowledge of pharmacology acquired in previous courses that include concepts of pharmacokinetics and pharmacodynamics
Teaching Methods
Lectures will be conducted according to the classical teaching method of face-to-face lectures. Moreover, interactive teaching methods will be included, such as case studies and/or clinical cases discussed and presented by the students, to stimulate their active participation and to optimize their learning abilities.
Practice exercises: none.
For the students with specific needs, who cannot attend in person the educational activities and applied for “Modalità Didattiche Inclusive” (Inclusive Teaching Methods), an adequate teaching material will be available for a fruitful self-study. If requested, the self-learning may be supported by tutoring activities or by supplementary activities, and by dedicated meetings, also online, with a flexible schedule according to the needs.
Practice exercises: none.
For the students with specific needs, who cannot attend in person the educational activities and applied for “Modalità Didattiche Inclusive” (Inclusive Teaching Methods), an adequate teaching material will be available for a fruitful self-study. If requested, the self-learning may be supported by tutoring activities or by supplementary activities, and by dedicated meetings, also online, with a flexible schedule according to the needs.
Assessment Methods
The teaching course of Toxicology and Pharmacovigilance (12 CFU) is composed by Toxicology (8 CFU) and Pharmacovilance (4 CFU). The 12 CFU conferred to the teaching course will be acquired in toto only after passing the total teaching course.
Two ongoing examinations (one for Toxicology and another for Pharmacovigilance) will be used to test the knowledge at the end of the handled program; alternatively, the preparation of the student will be verified through an oral exam during one of the official exam sessions.
Ongoing examinations: they are writing tests constituted by multiple choice questions. The tests can be only performed by students who reach the 75% of attendance to the lessons. The tests concern the handled program and the book texts/chapters indicated for reading during the course. Both two tests will will be composed by 30 multiple choices questions and an additional question will be added to have the highest quotation (30/30 cum laude).
The student can choose whether:
1. to split the teaching course passing the ongoing testes of each part, being understood that passing each part does not imply the acquisition of the corresponding CFU and that the right to acquire the total CFU attributed to the teaching course is linked to the condition of passing all the modules composing the teaching course;
2. do not split the teaching course by passing an integrated exam during one of the official exam sessions. In this case, the student will only do one integrated exam, including indeed all the component parts of the teaching course, and passing this exam will allow the acquisition of the total CFU attributed to the teaching course.
Appropriate examination methods are planned for students who fall under the categories for Specific Learning Disorders (SLD) and Special Educational Needs (SEN).
Two ongoing examinations (one for Toxicology and another for Pharmacovigilance) will be used to test the knowledge at the end of the handled program; alternatively, the preparation of the student will be verified through an oral exam during one of the official exam sessions.
Ongoing examinations: they are writing tests constituted by multiple choice questions. The tests can be only performed by students who reach the 75% of attendance to the lessons. The tests concern the handled program and the book texts/chapters indicated for reading during the course. Both two tests will will be composed by 30 multiple choices questions and an additional question will be added to have the highest quotation (30/30 cum laude).
The student can choose whether:
1. to split the teaching course passing the ongoing testes of each part, being understood that passing each part does not imply the acquisition of the corresponding CFU and that the right to acquire the total CFU attributed to the teaching course is linked to the condition of passing all the modules composing the teaching course;
2. do not split the teaching course by passing an integrated exam during one of the official exam sessions. In this case, the student will only do one integrated exam, including indeed all the component parts of the teaching course, and passing this exam will allow the acquisition of the total CFU attributed to the teaching course.
Appropriate examination methods are planned for students who fall under the categories for Specific Learning Disorders (SLD) and Special Educational Needs (SEN).
Texts
- Casarett & Doull: ELEMENTI DI TOSSICOLOGIA. Casa Editrice Ambrosiana
- Balduini e Costa: TOSSICOLOGIA GENERALE E APPLICATA AI FARMACI. Ed EDRA
- Govoni - Spampinato - Navarra AAVV: FARMACOLOGIA. Ed: Casa Editrice Ambrosiana; II Ed., 2023
- Balduini e Costa: TOSSICOLOGIA GENERALE E APPLICATA AI FARMACI. Ed EDRA
- Govoni - Spampinato - Navarra AAVV: FARMACOLOGIA. Ed: Casa Editrice Ambrosiana; II Ed., 2023
Contents
The course is structured in different sections. For pharmacovigilance, the molecular mechanisms that regulate drug-drug interactions will be first described and explained, and then the procedures and legislation currently used in the practice will be analysed to define the activities directed toward identifying, assessing, understanding and preventing adverse effects or any other problem related to the use of medicines.
In the section on general toxicology, biotransformation reactions and the toxic potential related to specific molecules or reactive groups are examined. In this section toxic mechanisms (apoptosis, mutagenesis, cancerogenesis, teratogenesis, etc.) are analyzed rather in detail. Another section concerns the organ toxicology, which deals with human organs and apparati as toxicity targets of drugs and molecules of different origins. The section on special toxicology deals with families of molecules examining their toxic potential, among them abuse substances, pesticides, environmental contaminants. Hints on food toxicity are also included.
In the section on general toxicology, biotransformation reactions and the toxic potential related to specific molecules or reactive groups are examined. In this section toxic mechanisms (apoptosis, mutagenesis, cancerogenesis, teratogenesis, etc.) are analyzed rather in detail. Another section concerns the organ toxicology, which deals with human organs and apparati as toxicity targets of drugs and molecules of different origins. The section on special toxicology deals with families of molecules examining their toxic potential, among them abuse substances, pesticides, environmental contaminants. Hints on food toxicity are also included.
Course Language
Italian
Degrees
Degrees
PHARMACY
Single-cycle Master’s Degree
5 years
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People
People (3)
Teaching staff
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