Provide in-depth knowledge about the biological basis of human diseases. Enable understanding of their pathogenetic mechanisms deep into the molecular level and investigate causal mechanisms of disorders of the fundamental organs and systems. Master the related essential medical terminology. This in order to create a path that orient the student toward professional interaction both with other health professionals and with patients / pharmacy customers.
Course Prerequisites
Biology, Anatomy, Physiology
Teaching Methods
Lectures supported by presentation of slides in Power Point. Key topics will be also supported by specific presentations, discussions and critical reading of the most recent research and review papers published in relevant journals the field.
Assessment Methods
Written Examination The student will be required to complete six open-ended questions (short essays), each worth 2.5 points, and ten multiple-choice questions, short definitions, or completions, each worth 1.5 points. Two midterm exams are scheduled for the academic year. Rapid tests will be offered during class hours, using the Wooclap platform for innovative teaching, to check the understanding of the topics proposed.
Texts
Suggested textbook Kumar V., Abbas A.K., Fausto N. Aster J.C. Robbins e Cotran - Le basi patologiche delle malattie Patologia generale Edra Editore - ISBN 8821447480 Patologia Generale - Eziologia, reazioni al danno e patologia delle funzioni cellulari non differenziate ( volume 1 ) + Funzioni differenziate di organi e sistemi ( volume 2 ) ISBN:9788823200005 Autori: Altucci - Berton - Moncharmont - Stivala Editore: Idelson - Gnocchi
Contents
The cell as the elementary patient. Cell injury. Necrosis. Apoptosis, autophagy, necroptosis, pyroptosis. General aetiology. Agents of endogenous diseases, genetic diseases: single gene mutations, chromosomal abnormalities, multifactorial diseases. Abiotic exogenous agents of disease. Physical and chemical disease agents. Elementary lesions. Degenerative injury. Inflammatory lesion. Immunology and immunologic injury. Tumours, biological characteristics and molecular oncology. Mixed lesions. Thrombus, atheroma.
