In the Biochemistry, Cellular Biochemistry and Cellular Biochemistry A modules the structure-function relationships of biological molecules, signalling pathways and metabolism are illustrated. Through the knowledge of how molecules and cells work, the chemical processes that define them, and how they interact with one another, students will get an in-depth insight into how cells and tissues function in health and sickness and how we can use that knowledge to understand the basis of treatments for diseases. Thus, the course is crucial and will pave the way for a molecular approach to physiology, pathology and pharmacology courses.
Course Prerequisites
A good knowledge of cell biology and the function of cellular organelles is required.
Teaching Methods
Face-to-face daily lectures will take place.
Teachers are available for any clarifications upon request.
Slides shown during lectures, detailed program and additional information are available during the course on the KIRO platform.
Assessment Methods
The exam is written including multiple choice questions and open questions on the topics covered in the lectures of the Biochemistry, Cellular Biochemistry and Molecular Biology modules. The exam lasts 90 min. During assessment it will be evaluated how the student has integrated the knowledge acquired in the three modules in which the course is divided as well as the level of achievement of the educational objectives in terms of knowledge and understanding. Communication skills and use of appropriate scientific terminology will be evaluated during assessment.
Texts
D. Nelson, M. Cox Lehninger PRINCIPLES OF BIOCHEMISTRY. 5th or 6th edition. ISBN-10: 1464109621; ISBN-13: 978-1464109621
J. Berg, J. Tymoczko, L. Stryer BIOCHEMISTRY 7th edition. ISBN-10: 071676766X; ISBN-13: 978-0716767664
Contents
Cellular biochemistry is developed considering the structure, organization and function of biological membranes. This is followed by the main signal transduction pathways, the molecular regulation of cell cycle, cell proliferation, differentiation and apoptosis. The biochemistry of hormones is then discussed. For selected course topics, chosen for their relevance and in light of recent scientific discoveries, students will be required to present and discuss in class articles published in international scientific journals.
