In the Biochemistry, Cellular Biochemistry and Molecular Biology modules the structure-function relationships of biological molecules, signalling pathways and metabolism are illustrated. Through the knowledge of how molecules and cells work, the chemical processes that define them, and how they interact with one another, students will get an in-depth insight into how cells and tissues function in health and sickness and how we can use that knowledge to understand the basis of treatments for diseases. Thus, the course is crucial and will pave the way for a molecular approach to physiology, pathology and pharmacology courses.
Course Prerequisites
In-depth knowledge of chemistry acquired during Basic Science Modules are propedeutic to the Biochemistry Course
Teaching Methods
Teaching consists of frontal lectures using Power-Point presentations. The slides shown during lectures, the detailed program and additional information are available in the KIRO platform. Lecturers are available for any clarifications upon request.
Assessment Methods
The exam is written including multiple choice questions and open questions on the topics covered in the lectures of the Biochemistry, Cellular Biochemistry and Molecular Biology modules. The exam lasts 90 min. During assessment it will be evaluated how the student has integrated the knowledge acquired in the three modules in which the course is divided as well as the level of achievement of the educational objectives in terms of knowledge and understanding. Communication skills and use of appropriate scientific terminology will be evaluated during assessment.
Texts
D. Nelson, M. Cox Lehninger PRINCIPLES OF BIOCHEMISTRY. 6th or 7th edition. ISBN-10: 1464109621; ISBN-13: 978-1464109621
J. Berg, J. Tymoczko, L. Stryer BIOCHEMISTRY 7th edition. ISBN-10: 071676766X; ISBN-13: 978-0716767664
Contents
Molecular biology is developed by putting special emphasis on the macromolecular processes of DNA replication and repair, RNA transcription and processing, protein synthesis, post-translational modifications and protein sorting. Aspects of regulation of gene expression and biotechnology are also discussed. For selected course topics, chosen for their relevance and in light of recent scientific discoveries, students will be required to present and discuss in class articles published in international scientific journals.
