Acquisition of structure, culture requirements and pathogenicity mechanisms of the most important microorganisms, with particular reference to oral cavity pathogens. Some topics will be addressed: correct use of antibiotics, antibiotic resistance; health care associated infections; notions of Clinical Microbiology (sepsis, UTIs, gastroenteritis, etc.); Role of biofilm in the development of plaque and caries.
Course Prerequisites
To study the teaching of Microbiology and Clinical Microbiology, in order to better follow the course, the student should have attended Human Anatomy, Biochemistry, Genetics and Physiology courses.
Teaching Methods
The course is based on lectures. There are no practical exercises. The teacher is available for clarification on the topics covered in class, by appointment (via email). Students will be provided with didactic material used in class.
Assessment Methods
The exam consists of a written test structured in 24 multiple choice questions. The teacher is available for clarification about the topics covered in class, by appointment to be booked (via email).
Texts
"Le basi della microbiologia" R.A. Harvey, P.C. Champe, B.D. Fisher Zanichelli
Contents
Epidemiological aspects of infectious diseases. The bacterial cell, basic components and accessory components (bacterial sporulation). Methods of sterilization and disinfection. Pathogenetic mechanisms. Microbiota in normal condition and disease. Host-pathogen interaction and pathogenesis of infectious diseases. Antibiotic and Antibiotic Resistance Mechanism: In vitro antimicrobial activity evaluation (antibiogram, MIC, MBC). Methods of clinical specimens sampling for microbiological analysis and their proper conservation. Direct and indirect diagnostic tools: microscopic and coltural methods, automated (maldi-tof mass spectrometry) and molecular systems (gene amplification), serology. General characters of bacteria of medical interest, with particular attention to staphylococci, streptococci and enterobacteria. Healthcare-associated infections (HAIs). Virus and Fungi: main structure and features. SPECIAL MICROBIOLOGY Enterobacteria, Pseudomonas aeruginosa, Acinetobacter baumannii, Staphylococci, Streptococci: - general characteristics - pathogenic action - clinical manifestations - laboratory diagnosis: useful methods for identification. Oral cavity tipical microorganisms: organization and pathogenetic role.
Course Language
Italian
More information
Examination Commission of the integrated course: Prof.ssa Francesca Zara Prof. Andrea Butera Prof.ssa Sara Cutti Prof.ssa Laura Antonia Marino
