ID:
501698
Duration (hours):
16
CFU:
2
SSD:
PATOLOGIA GENERALE
Year:
2025
Overview
Date/time interval
Secondo Semestre (02/03/2026 - 19/06/2026)
Syllabus
Course Objectives
The aim of the course is to introduce students to the causes and mechanisms underlying pathological processes.
The course will allow the student to obtain a basic knowledge of etiology and pathogenesis of human diseases, of the main cellular and tissue injuries and of the response to damage, of the molecular and cellular basis of chronic and acute inflammation and of oncology (etiology, pathogenesis, transformation, progression and metastasis).
At the end of the course the student will be able to understand the causes of the pathogenic processes, the fundamental mechanisms common to the pathogenic processes and the specific and non-specific responses of the organism to the injury.
The course will allow the student to obtain a basic knowledge of etiology and pathogenesis of human diseases, of the main cellular and tissue injuries and of the response to damage, of the molecular and cellular basis of chronic and acute inflammation and of oncology (etiology, pathogenesis, transformation, progression and metastasis).
At the end of the course the student will be able to understand the causes of the pathogenic processes, the fundamental mechanisms common to the pathogenic processes and the specific and non-specific responses of the organism to the injury.
Course Prerequisites
Understanding the topics covered in the General Pathology module requires a knowledge of the animal eukaryotic cell biology, the main biochemical processes and macromolecules involved, the main human anatomical districts and physiological functions. These skills can be acquired by attending and studying the courses that take place in the first semester of the first year.
The comprehension of the topics covered in the General Pathology module also requires basics of immunology provided by the high school.
Teaching Methods
Lectures, self-assessment test, using multimedia tools.
Assessment Methods
The learning test will take place in written form and will include 31 multiple choice questions (0.5 points/question) and 2 open questions (7.5 points/question). The duration of the test will be 90 minutes.
Texts
G.M. Pontieri-Elementi di Patologia generale & Fisiopatologia generale- IV edizione-Piccin
The slides of the lectures will be available in Kiro site.
The slides of the lectures will be available in Kiro site.
Contents
Introduction to General Pathology: homeostasis, etiology and pathogenesis. Immune system introduction.
Acquired etiologic factors: chemical agents (ethanol, tobacco smoke, metals, pneumoconiosis); physical agents (thermal injuries, non-ionizing radiations); nutrition.
Cellular adaptations: atrophy, hypertrophy, hyperplasia, metaplasia.
Intracellular accumulations: water and electrolytes, lipids (cholesterol and triglycerides).
Cell injury and cell death: causes, general biochemical mechanisms; necrosis, apoptosis and autophagy; senescence.
Acute inflammation: vascular changes; cellular events; chemical mediators; outcomes of acute inflammation (resolution, fibrosis).
Chronic inflammation: definition and causes, persistence of injurious agents (non-specific chronic inflammation, chronic suppurative inflammation), primary chronic inflammation (granulomatous diseases).
Systemic effects of inflammation: acute phase reactions, fever.
Healing and repair: wound healing.
Neoplasia: definitions and nomenclature, characteristics of benign and malignant neoplasms (differentiation and anaplasia, rate of growth, local invasion and metastasis); epidemiology (cancer incidence, geographic and environmental factors, heredity); molecular basis of cancer (oncogenes, cancer-suppressor genes); biology of tumor growth (kinetic, angiogenesis, tumor progression, mechanisms of invasion and metastasis); etiology of cancer (chemical, physical and microbial carcinogenesis)
Acquired etiologic factors: chemical agents (ethanol, tobacco smoke, metals, pneumoconiosis); physical agents (thermal injuries, non-ionizing radiations); nutrition.
Cellular adaptations: atrophy, hypertrophy, hyperplasia, metaplasia.
Intracellular accumulations: water and electrolytes, lipids (cholesterol and triglycerides).
Cell injury and cell death: causes, general biochemical mechanisms; necrosis, apoptosis and autophagy; senescence.
Acute inflammation: vascular changes; cellular events; chemical mediators; outcomes of acute inflammation (resolution, fibrosis).
Chronic inflammation: definition and causes, persistence of injurious agents (non-specific chronic inflammation, chronic suppurative inflammation), primary chronic inflammation (granulomatous diseases).
Systemic effects of inflammation: acute phase reactions, fever.
Healing and repair: wound healing.
Neoplasia: definitions and nomenclature, characteristics of benign and malignant neoplasms (differentiation and anaplasia, rate of growth, local invasion and metastasis); epidemiology (cancer incidence, geographic and environmental factors, heredity); molecular basis of cancer (oncogenes, cancer-suppressor genes); biology of tumor growth (kinetic, angiogenesis, tumor progression, mechanisms of invasion and metastasis); etiology of cancer (chemical, physical and microbial carcinogenesis)
Course Language
Italian
More information
Students can contact the teacher by e-mail to ask for clarification on the content of the lessons and on the study material or to request an appointment.
The teacher will provide the learning test correction and will be always available for any clarifications.
arianna.palladini@unipv.it
The teacher will provide the learning test correction and will be always available for any clarifications.
arianna.palladini@unipv.it
Degrees
Degrees
BIOMEDICAL LABORATORY TECHNIQUES
Bachelor’s Degree
3 years
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