The Human Physiology course is designed to teach the main physiological processes that underlie the different systems of the human body. By the end of the course, the student will have acquired a basic knowledge of the functioning of the major organs and systems of the human body and the control systems that regulate their activity.
Course Prerequisites
A good knowledge of elements of anatomy and biochemistry with particular reference to topics directly related to motor activity is a basic prerequisite.
Teaching Methods
The course is organized in lectures
Assessment Methods
The final assessment of learning will take the form of a written examination covering the topics of the programme taught in class. The final examination will consist of 30 multiple-choice questions and will be completed in 40 minutes. There are no penalties (deduction of marks) for incorrect answers.
Texts
FISIOLOGIA - W.J. German and C.L. Stanfield. Edises Principi di Fisiologia - L. Zocchi. Edises Fisiologia dell'Uomo. edi-ermes
Contents
Human Physiology Program (5 CFU)
1. Introduction to physiology General concepts Organs and tissues
2. Physiology of the cell Cell membrane and membrane proteins (structural proteins, receptors, enzymes, transport proteins) Membrane transport Cell communication and intracellular signaling pathways Membrane potential Action potential
3. Nervous system: Central and peripheral nervous system Structure and function of neurons Graded potentials, action potentials and their propagation Synapses and neurotransmitters Somatosensory system: receptors and ascending pathways Organization of the central nervous system: brainstem, cerebellum, cerebral cortex, basal ganglia and spinal cord Spinal reflexes (direct myotatic, reverse myotatic, nociceptive flexion reflex or flexor withdrawal reflex) Voluntary movements and their control Posture and its control (proprioceptive system, vestibular system and visual system) Autonomic nervous system
4. Muscle physiology Skeletal muscle Organization of skeletal muscle tissue Mechanism of contraction (excitation-contraction coupling) Neuromuscular junction Types of contraction Determinants of muscle force Determinants of shortening velocity Muscle fiber types Motor units and order of recruitment Muscle heterogeneity and plasticity Smooth muscle: characteristics and contraction mechanism
5. Cardiovascular System Blood and its components, Blood Vessels and Heart Functional properties of cardiac tissue Electrical activity of the heart: pacemaker cells, conduction system, action potentials Cardiac muscle cell contraction Cardiac cycle: changes in atrial, ventricular, aortic pressure and ventricular volume Cardiac output and its control Structure and function of blood vessels.
6. Respiratory system Basics of functional anatomy Lung ventilation: pressure gradients, surfactant, resistance Lung volumes Ventilation per minute and alveolar ventilation Gas exchanges Oxygen and carbon dioxide transport Haemoglobin dissociation curve Nervous and chemical regulation of respiration
7. Renal physiology Basics of functional anatomy and exchange processes Glomerular filtration and its regulation Reabsorption and secretion Renal clearance Water reabsorption (ADH hormone and Aldosterone) Control of acid-base balance
Course Language
Italian
More information
The Professor is always available by e-mail and welcomes students to his office at the Department of Molecular Medicine of the University of Pavia, via Forlanini 6, 27100 Pavia. It is advisable to make an appointment.